Biopharm Blended Cellulose Cartridge Filters0 pages

BBC Cartridge Filters
Blended Cellulose Membrane

Applications
Pre-filtration to increase the life of expensive final filters
Final filtration — reduce bacteria counts and particle levels
Typical Fluid Streams:
Reagents/Standards
Animal Serums
Human Serums/Albumin
Culture Media
Fermentation Products

Dimensions
Length

BBC filters are used for prefiltration and clarification applications in
biopharmaceutical processing. Applications include bacteria and
particulate removal in cell culture media, plasma products, serum,
SVPs, LVPs and other biological products. The filter elements are
100% integrity tested during production.
Blended cellulose membranes are particularly suited for the
filtration of products that contain elements that can adsorb to
the media, such as preservatives and proteins. The lower binding
characteristics of the membranes make them a good choice for
filtration of valuable protein solutions such as MAb solutions,
serum and other biologicals.

Construction Materials
Filtration Media

Blended Cellulose Membrane

Media Support

Polypropylene

End Caps

Polypropylene

Center Core

Polypropylene

Outer Support Cage

Polypropylene

Sealing Method

Thermal Bonding

O-rings

Buna, Viton® (or FKM), EP, Silicone,
FEP Encapsulated Silicone, FEP
Encapsulated Viton (or FKM)

2.75 in. (7.0 cm) nominal

Filtration Area

BBC cartridge filters are hydrophilic and manufactured with
blended cellulose membrane. The process creates a thick
membrane with very high loading capacity and high flow rates.
The blended cellulose material is very low protein binding and
allows protein rich solutions to pass with little impact on protein
content.

5 to 40 in. (12.7 to 101.6 cm) nominal

Outside Diameter

7.0 ft2 (0.65 m2) per 10 in. length

Maximum Operating Parameters
Differential Pressure
•t Forward

50 psid (3.4 bard) at 20 °C (68 °F)

•t Reverse

40 psid (2.7 bard) at 20 °C (68 °F)

Operating Temperature
Recommended
Changeout Pressure

82 °C (180 °F) at 10 psid
(0.69 bard) in water
35 psid (2.4 bard)

Sanitization/Sterilization
Filtered Hot Water

90 °C (194 °F), 30 minutes, multiple
cycles, max 3 psid forward flow

Autoclave

121 °C (250 °F), 30 min, multiple cycles

In-line Steam

135 °C (275 °F), 30 min, multiple cycles

For all elevated temperature procedures above, a stainless steel
support ring is required.
Chemical Sanitization
Performed using industry standard concentrations of hydrogen
peroxide, paracetic acid, and other selected chemicals.

Total Performance

Critical Process Filtration, Inc. is a vertically integrated
manufacturer of filtration products to industries in which
filtration is considered a critical part of the manufacturing
process. We supply a complete line of products and services to
help you cost effectively satisfy all your filtration requirements
from a single source.

Biopharmaceutical Grade

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