Corning® Gentest? Pre-coated PAMPA Plate System0 pages
Corning® Gentest™ Pre-coated PAMPA
Plate System
A 96 well permeable support system with a filter plate
pre-coated with structured layers of phospholipids
Features
w tStable, pre-coated PAMPA plate is
highly reproducible
w tImproved assay predictability over
traditional PAMPA
w tReduced mass retention of
compounds
Drug compounds are screened for their oral absorption potential early in the drug discovery
process in order to eliminate poor performers and to identify candidates that need to be
modified. Parallel artificial membrane permeability assays (PAMPA) have become a very
useful tool for predicting in vivo drug permeability and are well-suited as a ranking tool
for the assessment of compounds with passive transport mechanisms. Use of the PAMPA
assay allows for ranking of compounds into a low or high classification, using UV VIS
spectroscopy or LC/MS.
The Corning Gentest Pre-Coated PAMPA Plate System is a 96 well permeable support
system with a filter plate that has been pre-coated with structured layers of phospholipids
and a matched receiver microplate. The Corning Gentest Pre-coated PAMPA Plate System
has been validated for use in PAMPA and comes ready to use in your assay.